Forensic Genomics

LEANGENE provides solutions for Forensic Laboratories using Illumina next-generation sequencing (NGS) technology. 

Illumina NGS technology and informatics deliver far more insight from forensic DNA than traditional methods, with a much higher resolution than ever before possible. More efficient answers with a greater degree of certainty.

NGS allows examiners to generate data that span the human genome and address a wider range of questions in a single, targeted assay. Moreover, NGS-generated STR allele calls are fully compatible with current database formats. Early studies provide a promising view of the advantages NGS brings to analysis of even the smallest, most compromised, and highly mixed evidentiary samples.

  NGS enables genetic analysis for large numbers of globally relevant STR markers and dense SNP sets in a single test.

  NGS can help labs produce high-quality forensic profiles for national DNA databases, with a faster turnaround.

With the power of NGS, you can extract maximum information from limited samples, get accurate, actionable clues that can help you find missing persons and solve criminal cases.

Genetic analysis can help identify victims of mass fatalities when traditional methods cannot be used, or fail to yield conclusive results. Because next-generation sequencing (NGS) has no relevant limit on the number of loci that can be simultaneously analyzed, you can extract the maximum amount of information from evidence or a known reference sample.

Conventional disaster victim identification methods include fingerprints and odontology. Labs also use molecular methods such as DNA analysis and mitochondrial DNA (mtDNA) sequencing with capillary electrophoresis. Sample types processed after a mass fatality event can include bone fragments, tissue, various personal effects containing DNA, and buccal swabs from relatives.