An integrated instruments catering for all types of laboratory, with the widest range of gel assays, controls and accessories.

LEANGENE introduses the Clinical Gel Electrophoresis Systems from Helena BioSciences.

Helena Biosciences produces the most comprehensive portfolio of world-class instrumentation, software and assays, encompassing manual and automated diagnostic systems.

Integrated range of gel assays: Serum Proteins, Urine Proteins, Immunofixation, Haemoglobins, Isoenzymes, Lipoproteins, Isoelectric Focusing (IEF).

SAS-MX & SAS-MX IF

sas mx 600x400IEF chamber

 

High performance with low prices

Established around the world for 40 years, SAS-MX is simple and reliable technology matched by an exceptionally wide range of assays, delivering high performance, accuracy and reproducibility.

The standard chamber comes with a heat shield for use in high-resolution applications and is available with an optional IEF chamber for isoelectric focusing.

SAS-MX isoelectric focusing (IEF) chamber is a straightforward equipment and consistent results with 40 years experience in clinical electrophoresis.

SAS-1+ / SAS-2

sas 1 600x400

Automated electrophoresis analyser/processor

Compact integrated electrophoresis solution for laboratories running 1200-6000 tests per year. 

SAS-1 Plus is the ideal choice for laboratories conducting 40-100 Serum Proteins per week. SAS-1 Plus is the ideal choice for laboratories conducting 40-100 Serum Proteins per week. Partnering the SAS-1 Plus, Helena Biosciences’ SAS-2 gel processing system is the ideal solution for small-to-medium sized laboratories.

SAS-2 automates the staining, destaining & drying of the gel, & is optimised to give extraordinary clarity of protein gels.

SAS-3 / SAS-4

sas 3 600x400

Automated compact electrophoresis analyser/processor

Powerful and versatile semi-automated gel electrophoresis analyser and gel processor for labs running 4000-30000 tests per year, supporting a wide range of gels.

SAS-3 is ideal for laboratories conducting 60-200 tests per week. The SAS-4 gel processor is the partner to SAS-3 electrophoresis analyser. SAS-4 automates the staining, destaining and drying of electrophoresis gels, and is optimised to provide extraordinary clarity of protein gels.

Integrated range of gel assays:

 

SERUM PROTEINS

  • SAS Serum Proteins: 5 band gel using an advanced gel formulation ensuring enhanced resolution and sensitivity within the Gamma region.
  • Serum Protein (Split Beta): 6 band gel for differentiation of ß1 and ß2 fractions. The Split Beta Gel uses an advanced gel formulation ensuring enhanced resolution and sensitivity within the Beta and Gamma regions.
  • Serum Proteins (High Resolution): By using high-resolution agarose electrophoresis, 15 or more proteins can be visualised in the serum. This superior resolution and sensitivity separates and detects proteins with similar electrophoretic mobilities.

 

URINE PROTEINS

  • Urine Protein Analysis: a unique and completely flexible approach to urine protein analysis and screening techniques. The applicator system ensures unconcentrated urine can be applied directly to the gel with the confidence of no protein loss.

 

IMMUNOFIXATION

  • Serum Immunofixation Electrophoresis(IFE): characterised by its enhanced sensitivity, ease of interpretation, quick test results and excellent resolution. The SAS-MX Immunofix kit allows profiling a patient sample in just over an hour with the use of colour coded antisera.
  • Urine Immunofixation Electrophoresis (IFE): a rapid sensitive and specific method for identifying proteins in urine, aiding in the diagnosis of proteinuria. Combining sensitivity and specificity the SAS-MX Urine IFE kit offers a rapid cost-effective method for urine IFEs.
  • Pentavalent Screen: allowing direct screening of serum and/or urine samples for monoclonal proteins either in place of standard screening methods or as a pre- IFE confirmation. 

 

HEMOGLOBINES

  • Acid Haemoglobin Gel: using an advanced gel formulation ensuring enhanced resolution and sensitivity for the confirmation of abnormal haemoglobin samples.
  • Alkaline Haemoglobin Gel: using an advanced formulation ensuring enhanced resolution and sensitivity for initial haemoglobin screening. 

 

ISOENZYMES

  • Alkaline Phosphatase: high resolution agarose electrophoresis method for separation of Alkaline Phosphatase isoenzymes providing excellent discrimination with enhanced separation of bone and liver fractions. The gel formulation ensures separation of the macrohepatic fraction from bone and liver.
  • CK/LD Isoenzymes: definitive laboratory testing for documentation of Acute Myocardial Infarction (AMI) includes Creatine Kinase (CK) isoenzyme studies in conjunction with Lactate Dehydrogenase (LD) isoenzymes.

 

LIPOPROTEINS

  • Lipoprotein Analysis: an assay for the added assessment of Coronary Heart Disease has become integral to the in depth use of cardiac patient scoring systems. The Lipoprotein electrophoresis assay is an excellent method for the phenotyping of lipoproteins giving additional patient information. 
  • Cholesterol Profile: designed for the assessment of cholesterol content of the major lipoprotein fractions. The excellent separations of the various cholesterol constituents are easily conducted without the need for additional separation techniques. The cholesterol profile assay separates into HDL, vLDL, LDL and Lp(a).
  • HDL Cholesterol: complements the Lipoprotein Kit for assessment of the cholesterol content of Alpha, Beta and pre-Beta components, recognised as HDL, vLDL and LDL.

 

ISOELECTRIC FOCUSING (IEF)

  • Transferrin IEF: Isoelectric Focusing coupled with immunoblotting discriminates between the various isoforms of Transferrin. The method can be used for no gap qualitative analysis of serum samples to determine dysfunction in glycosilation of serum proteins found in genetic disorders/alcohol abuse.
  • Alpha-1-Antitrypsin: intended for the identification of genetic variants in human serum by a combination of iso-electric focusing and immunofixation. The Alpha-1- Antitrypsin (α1-AT) variants are separated according to iso- electric point in an agarose IEF gel.
  • IgG IEF: intended for the identification of IgG-specific oligoclonal banding in serum and cerebro-spinal fluid (CSF) by agarose gel isoelectric focusing and immunoblotting. This technique is considered to be the “Gold Standard” method for the determination of intrathecal IgG synthesis in the clinical diagnosis of multiple sclerosis and offers advantages over other methods such as IgG quotient, blood-CSF barrier function, direct staining and in-gel fixation methods. Many studies have shown that direct silver staining techniques exhibit reduced sensitivity and specificity to IgG.

 

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